Complement C3

Human GmbH
Proteins
Brief Description
Complement C3 (C3c) is the central point of the classic and alternative complement pathway. C3c is a constituent of C5 convertase. On activation split products of C3c have important biological functions. C3b is an opsonin and involved in immune adherence, C3a is an anaphylatoxin and a chemotoxin. C3c behaves also like an acute phase protein, therefore increased levels may be found in acute inflammatory reactions. Decreased levels are reported in complex diseases, recurrent immune infections with pyrogenic bacteria, various glomerulonephritides and in congenital deficiencies.
Immunoturbidimetric test for the quantitative determination of complement C3 (C3c) in human serum.